زائر
amxiiin tihydate
(a mx i si' in)
Amxi, Amxi Pediati Dps, Ap-Amxi (AN), Nvamxin (AN), N-Amxi (AN), Timx, Timx Pediati Dps, Wymx
Pegnany ategy B
Dg ass
Antibiti, peniiin–ampiiin type
Theapeti atins
Bateiida: inhibits synthesis f e wa f sensitive ganisms, asing e death.
Indiatins
· Infetins de t sseptibe stains f Haemphis infenzae, E. i, Ptes miabiis, Neisseia gnheae, Stepts pnemniae, stepti, nnpeniiinase-pding staphyi
· Heibate pyi infetin in mbinatin with the agents
· Pst-expse pphyaxis against Bais anthais
· nabeed se: hamydia tahmatis in pegnany
ntaindiatins and atins
· ntaindiated with aegies t peniiins, ephaspins, the aegens.
· se atisy with ena disdes, atatin.
Avaiabe fms
hewabe tabets--125, 250 mg; tabets--500, 875 mg; apses--250, 500 mg; pwde f a sspensin--50 mgm; 125 mg5 m, 200 mg5 m, 250 mg5 m, 400 mg5 m
Avaiabe in a pepaatins ny.
Dsages
ADTS AND PEDIATI PATIENTS > 20 KG
· Is, G infetins, skin and sft-tisse infetins: 250–500 mg P q 8 h 875 mg P bid.
· Pst-expse anthax pphyaxis: 500 mg P tid.
· we espiaty infetins: 500 mg P q 8 h 875 mg P bid.
· nmpiated gna infetins: 3 g amxiiin with 1 g pbeneid P.
· . tahmatis in pegnany: 500 mg P tid f 7 days 875 mg P bid.
· Peventin f SBE: Denta, a, ppe espiaty pedes: 2 g 1 h befe pede.
· GI G pedes: 2 g ampiiin ps 1.5 mgkg gentamiin IM IV 30 min befe pede, fwed by 1 g amxiiin; f w-isk patients, 2 g 1 h befe pede.
· H. pyi: 1 g bid with aithmyin 500 mg bid and anspaze 30 mg bid f 14 days.
PEDIATI PATIENTS < 20 KG<SPAN>
· Is, G infetins, skin, and sft-tisse infetins: 20–40 mgkgday P in divided dses q 8 h.
· Pst-expse anthax pphyaxis: 80 mgkgday P divided int 3 dses.
· we espiaty infetins: 40 mgkgday P in divided dses q 8 h.
· Peventin f SBE: Denta, a, ppe espiaty pedes: 50 mgkg 1 h befe pede.
· GI G pedes: 50 mgkg ampiiin ps 2 mgkg gentamiin IM IV 30 min befe pede fwed by 25 mgkg amxiiin. F mdeate-isk patients, 50 mgkg P 1 h befe pede.
Phamakinetis
te
nset
Peak
Datin
a
Vaies
1 h
6–8 h
Metabism: T12: 1–1.4 h
Distibtin: sses paenta; passes int beast mik
Exetin: nhanged in the ine
Advese effets
· NS: ethagy, hainatins, seizes
· GI: Gssitis, stmatitis, gastitis, se mth, fy tnge, bak “haiy” tnge, nasea, vmiting, diahea, abdmina pain, bdy diahea, enteitis, psedmembans itis, nnspeifi hepatitis
· G: Nephitis
· Hematgi: Anemia, thmbytpenia, ekpenia, netpenia, pnged beeding time
· Hypesensitivity: ash, feve, wheezing, anaphyaxis
· the: Speinfetins--a and eta mniiasis, vaginitis
Inteatins
Dg-dg
· Ineased effet with pbeneid
· Deeased effetiveness with tetayines, hampheni
· Deeased effiay f a ntaeptives
Dg-fd
· Deayed eded GI absptin with fd
Nsing nsideatins
Assessment
· Histy: Aegies t peniiins, ephaspins, the aegens; ena disdes; atatin
· Physia: te infeted aea; skin , esin; , adventitis snds; bwe snds; B, ive and ena fntin tests, sem eetytes, Ht, inaysis
Inteventins
· te infeted aea pi t teatment; ete aea if espnse is nt as expeted.
· Give in a pepaatins ny; absptin may be affeted by pesene f fd; dg shd be taken 1 h befe 2 h afte meas.
· ntine theapy f at east 2 days afte signs f infetin have disappeaed; ntinatin f 10 f days is emmended.
· se tisteids, antihistamines f skin eatins.
Teahing pints
· Take this dg and the k. The dg shd be taken n an empty stmah, 1 h befe 2 h afte meas.
· Take the f se f theapy; d nt stp bease y fee bette.
· This antibiti is speifi f this pbem and shd nt be sed t sef-teat the infetins.
· These side effets may : nasea, vmiting, GI pset (sma feqent meas may hep); diahea; se mth (feqent mth ae may hep).
· ept nsa beeding bising, se that, feve, ash, hives, sevee diahea, diffity beathing.
Advese effets in Itai ae mst mmn; thse in Bd ae ife-theatening.
(a mx i si' in)
Amxi, Amxi Pediati Dps, Ap-Amxi (AN), Nvamxin (AN), N-Amxi (AN), Timx, Timx Pediati Dps, Wymx
Pegnany ategy B
Dg ass
Antibiti, peniiin–ampiiin type
Theapeti atins
Bateiida: inhibits synthesis f e wa f sensitive ganisms, asing e death.
Indiatins
· Infetins de t sseptibe stains f Haemphis infenzae, E. i, Ptes miabiis, Neisseia gnheae, Stepts pnemniae, stepti, nnpeniiinase-pding staphyi
· Heibate pyi infetin in mbinatin with the agents
· Pst-expse pphyaxis against Bais anthais
· nabeed se: hamydia tahmatis in pegnany
ntaindiatins and atins
· ntaindiated with aegies t peniiins, ephaspins, the aegens.
· se atisy with ena disdes, atatin.
Avaiabe fms
hewabe tabets--125, 250 mg; tabets--500, 875 mg; apses--250, 500 mg; pwde f a sspensin--50 mgm; 125 mg5 m, 200 mg5 m, 250 mg5 m, 400 mg5 m
Avaiabe in a pepaatins ny.
Dsages
ADTS AND PEDIATI PATIENTS > 20 KG
· Is, G infetins, skin and sft-tisse infetins: 250–500 mg P q 8 h 875 mg P bid.
· Pst-expse anthax pphyaxis: 500 mg P tid.
· we espiaty infetins: 500 mg P q 8 h 875 mg P bid.
· nmpiated gna infetins: 3 g amxiiin with 1 g pbeneid P.
· . tahmatis in pegnany: 500 mg P tid f 7 days 875 mg P bid.
· Peventin f SBE: Denta, a, ppe espiaty pedes: 2 g 1 h befe pede.
· GI G pedes: 2 g ampiiin ps 1.5 mgkg gentamiin IM IV 30 min befe pede, fwed by 1 g amxiiin; f w-isk patients, 2 g 1 h befe pede.
· H. pyi: 1 g bid with aithmyin 500 mg bid and anspaze 30 mg bid f 14 days.
PEDIATI PATIENTS < 20 KG<SPAN>
· Is, G infetins, skin, and sft-tisse infetins: 20–40 mgkgday P in divided dses q 8 h.
· Pst-expse anthax pphyaxis: 80 mgkgday P divided int 3 dses.
· we espiaty infetins: 40 mgkgday P in divided dses q 8 h.
· Peventin f SBE: Denta, a, ppe espiaty pedes: 50 mgkg 1 h befe pede.
· GI G pedes: 50 mgkg ampiiin ps 2 mgkg gentamiin IM IV 30 min befe pede fwed by 25 mgkg amxiiin. F mdeate-isk patients, 50 mgkg P 1 h befe pede.
Phamakinetis
te
nset
Peak
Datin
a
Vaies
1 h
6–8 h
Metabism: T12: 1–1.4 h
Distibtin: sses paenta; passes int beast mik
Exetin: nhanged in the ine
Advese effets
· NS: ethagy, hainatins, seizes
· GI: Gssitis, stmatitis, gastitis, se mth, fy tnge, bak “haiy” tnge, nasea, vmiting, diahea, abdmina pain, bdy diahea, enteitis, psedmembans itis, nnspeifi hepatitis
· G: Nephitis
· Hematgi: Anemia, thmbytpenia, ekpenia, netpenia, pnged beeding time
· Hypesensitivity: ash, feve, wheezing, anaphyaxis
· the: Speinfetins--a and eta mniiasis, vaginitis
Inteatins
Dg-dg
· Ineased effet with pbeneid
· Deeased effetiveness with tetayines, hampheni
· Deeased effiay f a ntaeptives
Dg-fd
· Deayed eded GI absptin with fd
Nsing nsideatins
Assessment
· Histy: Aegies t peniiins, ephaspins, the aegens; ena disdes; atatin
· Physia: te infeted aea; skin , esin; , adventitis snds; bwe snds; B, ive and ena fntin tests, sem eetytes, Ht, inaysis
Inteventins
· te infeted aea pi t teatment; ete aea if espnse is nt as expeted.
· Give in a pepaatins ny; absptin may be affeted by pesene f fd; dg shd be taken 1 h befe 2 h afte meas.
· ntine theapy f at east 2 days afte signs f infetin have disappeaed; ntinatin f 10 f days is emmended.
· se tisteids, antihistamines f skin eatins.
Teahing pints
· Take this dg and the k. The dg shd be taken n an empty stmah, 1 h befe 2 h afte meas.
· Take the f se f theapy; d nt stp bease y fee bette.
· This antibiti is speifi f this pbem and shd nt be sed t sef-teat the infetins.
· These side effets may : nasea, vmiting, GI pset (sma feqent meas may hep); diahea; se mth (feqent mth ae may hep).
· ept nsa beeding bising, se that, feve, ash, hives, sevee diahea, diffity beathing.
Advese effets in Itai ae mst mmn; thse in Bd ae ife-theatening.