زائر
azithmyin
(ay zi th my' sin)
Zithmax
Pegnany ategy B
Dg ass
Maide antibiti
Theapeti atins
Bateistati bateiida in sseptibe bateia.
Indiatins
· Teatment f we espiaty tat infetins: ate bateia exaebatins f PD de t H. infenzae, Maxea atahais, S. pnemniae; mmnity-aqied pnemnia de t S. pnemniae, H. infenzae
· Teatment f we espiaty tat infetins: stepta phayngitistnsiitis de t Stepts pygenes in thse wh annt take peniiins
· Teatment f nmpiated skin infetins de t Staphys aes, S. pygenes, Stepts agaatiae
· Teatment f nngna ethitis and eviitis de t . tahmatis; teatment f PID
· Teatment f titis media ased by H. infenzae, M. atahais, S. pnemniae in hiden > 6 m
· Teatment f phayngitistnsiitis in hiden > 2 y wh annt se fist-ine theapy
· Peventin and teatment f disseminated Mybateim avim mpex (MA) in patients with advaned AIDS
· nabeed ses: nmpiated gna infetins ased by N. gnheae; gna phayngitis ased by N. gnheae; hamydia infetins ased by . tahmatis; pphyaxis afte sexa attak
ntaindiatins and atins
· ntaindiated with hypesensitivity t azithmyin, eythmyin, any maide antibiti.
· se atisy with gnhea syphiis, psedmembans itis, hepati ena impaiment, atatin.
Avaiabe fms
Tabets--250, 600 mg; pwde f injetin--500 mg; pwde f a sspensin--100 mg5 m, 200 mg5 m, 1 gpaket
Dsages
ADTS
· Mid t mdeate ate bateia exaebatins f PD, pnemnia, phayngitistnsiitis (as send-ine): 500 mg P singe dse n fist day, fwed by 250 mg P daiy n days 2–5 f a tta dse f 1.5 g 500 mgday P f 3 days.
· Nngna ethitis and eviitis de t . tahmati: A singe 1-g P dse.
· Gna ethitis and eviitis: A singe dse f 2 g P.
· Disseminated MA infetins:
Peventin: 1,200 mg P taken ne weeky.
Teatment: 600 mgday P with etambt.
PEDIATI PATIENTS
· titis media: Initiay 10 mgkg P as a singe dse, then 5 mgkg n days 2–5 30 mgkg P as a singe dse.
· mmnity-aqied pnemnia: 10 mgkg P as a singe dse n fist day, then 5 mgkg P n days 2–5.
· Phayngitistnsiitis: 12 mgkgday P n days 1–5.
Phamakinetis
te
nset
Peak
Datin
a
Vaies
2.5–3.2 h
24 h
Metabism: T12: 11–48 h
Distibtin: sses paenta; passes int beast mik
Exetin: nhanged in biiay exetin and ine
Advese effets
· NS: Dizziness, headahe, vetig, smnene, fatige
· GI: Diahea, abdmina pain, nasea, dyspepsia, fatene, vmiting, meena, psedmembans itis
· the: Speinfetins, angiedema, ash, phtsensitivity, vaginitis
Inteatins
Dg-dg
· Deeased sem eves and effetiveness f azithmyin with aminm and magnesim-ntaining antaids
· Pssibe ineased effets f thephyine
· Pssibe ineased antiagant effets f wafain
Dg-fd
· Fd geaty deeases the absptin f azithmyin
Nsing nsideatins
Assessment
· Histy: Hypesensitivity t azithmyin, eythmyin, any maide antibiti; gnhea syphiis, psedmembans itis, hepati ena impaiment, atatin
· Physia: Site f infetin; skin , esins; ientatin, GI tpt, bwe snds, ive evaatin; te and sensitivity tests f infetin, inaysis, ive and ena fntin tests
Inteventins
· te site f infetin befe theapy.
· Administe n an empty stmah--1 h befe 2–3 h afte meas. Fd affets the absptin f this dg.
· nse patients being teated f STDs abt apppiate peatins and additina theapy.
Teahing pints
· Take this dg n an empty stmah--1 h befe 2–3 h afte meas; it shd neve be taken with fd. Take the f se pesibed. D nt take with antaids.
· These side effets may : stmah amping, dismft, diahea; fatige, headahe (mediatin may hep); additina infetins in the mth vagina (nst with heath ae pvide f teatment).
· ept sevee watey diahea, sevee nasea vmiting, ash ithing, mth ses, vagina ses.
Advese effets in Itai ae mst mmn; thse in Bd ae ife-theatening.
(ay zi th my' sin)
Zithmax
Pegnany ategy B
Dg ass
Maide antibiti
Theapeti atins
Bateistati bateiida in sseptibe bateia.
Indiatins
· Teatment f we espiaty tat infetins: ate bateia exaebatins f PD de t H. infenzae, Maxea atahais, S. pnemniae; mmnity-aqied pnemnia de t S. pnemniae, H. infenzae
· Teatment f we espiaty tat infetins: stepta phayngitistnsiitis de t Stepts pygenes in thse wh annt take peniiins
· Teatment f nmpiated skin infetins de t Staphys aes, S. pygenes, Stepts agaatiae
· Teatment f nngna ethitis and eviitis de t . tahmatis; teatment f PID
· Teatment f titis media ased by H. infenzae, M. atahais, S. pnemniae in hiden > 6 m
· Teatment f phayngitistnsiitis in hiden > 2 y wh annt se fist-ine theapy
· Peventin and teatment f disseminated Mybateim avim mpex (MA) in patients with advaned AIDS
· nabeed ses: nmpiated gna infetins ased by N. gnheae; gna phayngitis ased by N. gnheae; hamydia infetins ased by . tahmatis; pphyaxis afte sexa attak
ntaindiatins and atins
· ntaindiated with hypesensitivity t azithmyin, eythmyin, any maide antibiti.
· se atisy with gnhea syphiis, psedmembans itis, hepati ena impaiment, atatin.
Avaiabe fms
Tabets--250, 600 mg; pwde f injetin--500 mg; pwde f a sspensin--100 mg5 m, 200 mg5 m, 1 gpaket
Dsages
ADTS
· Mid t mdeate ate bateia exaebatins f PD, pnemnia, phayngitistnsiitis (as send-ine): 500 mg P singe dse n fist day, fwed by 250 mg P daiy n days 2–5 f a tta dse f 1.5 g 500 mgday P f 3 days.
· Nngna ethitis and eviitis de t . tahmati: A singe 1-g P dse.
· Gna ethitis and eviitis: A singe dse f 2 g P.
· Disseminated MA infetins:
Peventin: 1,200 mg P taken ne weeky.
Teatment: 600 mgday P with etambt.
PEDIATI PATIENTS
· titis media: Initiay 10 mgkg P as a singe dse, then 5 mgkg n days 2–5 30 mgkg P as a singe dse.
· mmnity-aqied pnemnia: 10 mgkg P as a singe dse n fist day, then 5 mgkg P n days 2–5.
· Phayngitistnsiitis: 12 mgkgday P n days 1–5.
Phamakinetis
te
nset
Peak
Datin
a
Vaies
2.5–3.2 h
24 h
Metabism: T12: 11–48 h
Distibtin: sses paenta; passes int beast mik
Exetin: nhanged in biiay exetin and ine
Advese effets
· NS: Dizziness, headahe, vetig, smnene, fatige
· GI: Diahea, abdmina pain, nasea, dyspepsia, fatene, vmiting, meena, psedmembans itis
· the: Speinfetins, angiedema, ash, phtsensitivity, vaginitis
Inteatins
Dg-dg
· Deeased sem eves and effetiveness f azithmyin with aminm and magnesim-ntaining antaids
· Pssibe ineased effets f thephyine
· Pssibe ineased antiagant effets f wafain
Dg-fd
· Fd geaty deeases the absptin f azithmyin
Nsing nsideatins
Assessment
· Histy: Hypesensitivity t azithmyin, eythmyin, any maide antibiti; gnhea syphiis, psedmembans itis, hepati ena impaiment, atatin
· Physia: Site f infetin; skin , esins; ientatin, GI tpt, bwe snds, ive evaatin; te and sensitivity tests f infetin, inaysis, ive and ena fntin tests
Inteventins
· te site f infetin befe theapy.
· Administe n an empty stmah--1 h befe 2–3 h afte meas. Fd affets the absptin f this dg.
· nse patients being teated f STDs abt apppiate peatins and additina theapy.
Teahing pints
· Take this dg n an empty stmah--1 h befe 2–3 h afte meas; it shd neve be taken with fd. Take the f se pesibed. D nt take with antaids.
· These side effets may : stmah amping, dismft, diahea; fatige, headahe (mediatin may hep); additina infetins in the mth vagina (nst with heath ae pvide f teatment).
· ept sevee watey diahea, sevee nasea vmiting, ash ithing, mth ses, vagina ses.
Advese effets in Itai ae mst mmn; thse in Bd ae ife-theatening.