زائر
دراسات التكافؤ الحيوي
bieqivaene test
Bieqivaene is a tem in phamakinetis sed t assess the
expeted in viv bigia eqivaene f tw ppietay pepaatins f a dg. If tw pdts ae said t be bieqivaent it means that they wd be expeted t be, f a intents and ppses, the same.
Bikett (2003) defined bieqivaene by stating that, "tw phamaetia pdts ae bieqivaent if they ae phamaetiay eqivaent and thei biavaiabiities (ate and extent f avaiabiity) afte administatin in the same ma dse ae simia t sh a degee that thei effets, with espet t bth effiay and safety, an be expeted t be essentiay the same. Phamaetia eqivaene impies the same amnt f the same ative sbstane(s), in the same dsage fm, f the same te f administatin and meeting the same mpaabe standads."
The nited states Fd and Dg Administatin (FDA) has defined bieqivaene as, "the absene f a signifiant diffeene in the ate and extent t whih the ative ingedient ative miety in phamaetia eqivaents phamaetia atenatives bemes avaiabe at the site f dg atin when administeed at the same ma dse nde simia nditins in an apppiatey designed stdy." (FDA, 2003)
اي ترجمه للعربي انا جاهزه ان شاء الله
منقول من موسوعة الوكيبيديا
تحياتــــــــــــــي
bieqivaene test
Bieqivaene is a tem in phamakinetis sed t assess the
expeted in viv bigia eqivaene f tw ppietay pepaatins f a dg. If tw pdts ae said t be bieqivaent it means that they wd be expeted t be, f a intents and ppses, the same.
Bikett (2003) defined bieqivaene by stating that, "tw phamaetia pdts ae bieqivaent if they ae phamaetiay eqivaent and thei biavaiabiities (ate and extent f avaiabiity) afte administatin in the same ma dse ae simia t sh a degee that thei effets, with espet t bth effiay and safety, an be expeted t be essentiay the same. Phamaetia eqivaene impies the same amnt f the same ative sbstane(s), in the same dsage fm, f the same te f administatin and meeting the same mpaabe standads."
The nited states Fd and Dg Administatin (FDA) has defined bieqivaene as, "the absene f a signifiant diffeene in the ate and extent t whih the ative ingedient ative miety in phamaetia eqivaents phamaetia atenatives bemes avaiabe at the site f dg atin when administeed at the same ma dse nde simia nditins in an apppiatey designed stdy." (FDA, 2003)
اي ترجمه للعربي انا جاهزه ان شاء الله
منقول من موسوعة الوكيبيديا
تحياتــــــــــــــي
