زائر
GINA, Spain, Api 29
The aspiin-ike agent tifsa may evese eay signs f diabetes amng thewise heathy bese patients,Dt_1
eseahes fnd Tifsa deeased fasting bd gse eves (P=0.03) and ineased insin seetin in a dse-dependent manne (P=0.04)..
These findings fm a sma inia tia appeaed t be eated t effets n insin-pding iset es athe than by ineasing insin sensitivity
**Expain t inteested patients that besity is assiated with insin esistane, whih an ead t type 2 diabetes.
**Nte that the dg sed in the stdy is sed as an antipateet agent in Epe and the aeas bt is nt avaiabe in the .S.
**Pint t that the effet appeas t be mediated thgh a diet inease in insin seetin and nt a hange in insin sensitivity.
The saiyate deivative tifsa, athgh nt avaiabe in the nited States, is widey sed as an antipateet dg in Epe and the aeas.
Athgh the ests waant fthe stdy, patients shd stik t the many pven teatments t nt bd sga and evese insin esistane, patiay diet and exeise, mmented Jhn Bse, M.D., Ph.D., f the nivesity f Nth aina at hape Hi and Ameian Diabetes Assiatin pesident f mediine and siene.
"I think it wd be extemey pemate t se this iniay," D. Bse said in an inteview. "We knw these nnsteida anti-infammaty dgs with ng-tem expse in sme patients an ead t kidney pbems and es."
Aspiin and the saiyates have been shwn t ede gse eves amng bth diabeti patients and thse with nma gse teane in sme bt nt a stdies.
Afte ne eent stdy shwed that a high-dse saiyate d evese insin esistane in besity, the eseahes anhed a dbe-bind, ss-ve stdy f the effets f tifsa n insin sensitivity and seetin in bese patients.
Tifsa eded fasting sem gse nentatins mpaed with baseine (95.8 at 600 mg and 94.2 at 900 mg vess 98.6 mgd, P=0.03).
Hemgbin A1 as dpped amng wmen with tifsa mpaed with baseine (4.6% f 600 mg and 4.4% f 900 mg vess 4.6% at baseine, P=0.04), bt thee was n simia dp amng mae patiipants (P=0.8